Bullet-Shaped Vesicular Stomatitis Virus
2010 February 5
In a latest online article in journal Science Ge et al. report a cryo-electron microscopy structure of a model rhabdovirus, a bullet-shaped vesicular stomatitis virus (VSV). Using their structural data they suggest a mechanism of VSV assembly in which the nucleocapsid spirals from the tip to become the helical trunk.
Cryo-EM structure showing the putative cytoplasmic tail of G protein binding to an M subunit through a thin linker. Image credits Science
Proposed mechanism by which the nucleocapsid ribbon generates the virion head, starting with its bullet tip.Image credits Science
Architectural representation of the virion trunk, rendered in 3D animation.
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Bullet-Shaped Vesicular Stomatitis Virus http://bit.ly/cdsy9Y #fisheye